Isomorphic and Eli Lilly Partner To Discover Molecule Therapeutics

Isomorphic Labs, a digital biology company with a mission to redefine drug discovery through the power of artificial intelligence, has announced a strategic research collaboration with Eli Lilly, an American pharmaceutical company headquartered in Indianapolis that combines caring and discovery to create medicines that improve people's lives all over the world. This is Isomorphic Labs' first pharmaceutical relationship with Eli Lilly.

Under the terms of the agreement, Isomorphic Labs will partner with Lilly to discover small molecule therapeutics against multiple targets and will receive an upfront cash payment of $45 million. Isomorphic Labs is eligible to receive up to $1.7 billion in performance-based milestone payments, excluding the upfront payment and any subsequent tiered royalties of up to low double digits on net sales, as per pharmabiz.

"We're thrilled to embark on this partnership and apply our proprietary technology platform, the next generation of AlphaFold, and access to massive computing power to Lilly's development programs," said Demis Hassabis, CEO and founder of Isomorphic Labs. "The focus we share on advancing groundbreaking drug design approaches and appreciation of state-of-the-art science makes this partnership particularly compelling."

Isomorphic Labs operates independently inside Alphabet, with its own committed resources and an exclusive focus on the application of artificial intelligence to drug discovery. The company is reinventing the entire drug development process from the ground up using an artificial intelligence-first approach, developing strong new predictive and generative models of biological events to forecast how medications will perform and designing new compounds.

Eli Lilly recently announced 'LillyDirect', a revolutionary digital healthcare experience for people in the United States suffering from obesity, migraines, and diabetes. It provides disease management resources, including as access to independent healthcare providers, personalized support, and direct home delivery of select Lilly medications via third-party pharmacy dispensing services.